Chlamydiaceae

The genus Chlamydia includes, among others, the human and animal pathogenic species C. pneumoniae, C. trachomatis and C. abortus.

For the production of the native antigen BA1371VSER, strain C. pneumoniae TWAR strain TW-183 is cultivated in cell culture (BGM cells) and the elementary and reticular bodies are prepared by ultra-centrifugation. For the production of the native antigen BA1372VSER, C.trachomatis is cultivated in Vero cell culture.

In case of C. pneumoniae a further purified native antigen is available – the COMC premium antigen BA1371VS . This antigen is prepared by detergent extraction of the reticular bodies to prepare chlamydial outer membrane complexes (COMCs). This premium antigen is highly recommended for the detection of IgG, IgM and IgA antibodies against C. pneumoniae.

Additionally, a recombinant C. trachomatis MOMP antigen BA1372VSR2 is available which is produced in E. coli, purified by chromatography in the presence of urea. Purity of ≥ 95 % is confirmed via SDS-PAGE (Coomassie staining) and the antigen is suitable for the detection of IgG, IgM and IgA antibodies against C. trachomatis.

Please let us know if you are interested in 0.25 mg test samples.