Cytomegalovirus is a genus of viruses that belongs to the family of Herpesviridae. Currently eight species have been described in this genus, including human Cytomegalovirus (HCMV, Human Herpesvirus 5, HHV-5). CMV infection during pregnancy can cause severe subsequent damages for the unborn child including micro encephalitis, so CMV belongs to the ToRCH screening panel. The native antigen is produced by cultivation of CMV strain Towne in HEL-299 cells. The extracted CMV antigen is purified by ultra-centrifugation and consists of purified virus particles and further virus components. The antigen is suitable for the detection of IgG and IgM antibodies against CMV.
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