Herpes Simplex Virus (HSV)
Herpes Simplex Virus 1 and 2 (HSV-1 and HSV-2), also known as Human Herpesvirus 1 and 2 (HHV-1 and HHV-2), are two members of the Herpesvirus family that infect humans. Typical diseases related to these two viruses are herpes simplex (HSV-1) or genital herpes (HSV-2) and Herpes Viruses are part of the ToRCH screening panel, especially during pregnancy. For the native antigens, Herpes Simplex Virus 1 (strain F) and Herpes Simplex Virus 2 (strain G) are cultivated in Vero cells and virus purification is performed by a two-step ultra-centrifugation. The antigens consists of virus particles and virus components and are suitable for the detection of IgG, IgM and IgA antibodies to HSV-1 or HSV-2 respectively. In addition two recombinant HSV antigens are available – HSV-1 glycoprotein and HSV-2 glycoprotein. Both antigens are produced in E. coli and purified by chromatography. These antigens are species specific for HSV-1 and HSV-2 in IgG assays and can therefore be used to differentiate between both viruses. Purity of ≥ 95 % is confirmed via SDS-PAGE (Coomassie staining).
Please let us know if you are interested in 0.25 mg test samples.
For antigen orders in the U.S., please contact our local sales partner The Binding Site Inc.