Tick-borne encephalitis (TBE) Virus

Tick-borne encephalitis Virus is a member of the genus of Flaviviruses and related with other Flaviviruses such as Dengue, Zika or the Hepatitis C Virus. The virus is transmitted via tick bite and can cause a severe encephalitis in humans.

Virion\Serion’s TBE Virus Envelope protein E (BA112R01) (Far Eastern subtype, strain Sofjin) is recombinantly produced in insect cells and highly purified by strep-tag affinity chromatography, which guarantees high quality and availability.

In addition, an optimized TBE Virus Envelope Protein E (BA112R02) is now available. The antigen is recombinantly produced in insect cells and is present in an oligomeric form, preserving relevant conformational epitopes. These characteristics provide a native-like antigen structure and support excellent performance in immunoassay applications. The optimized antigen is also suitable for CLIA-based assay formats.

Together with our Tick-borne encephalitis (TBE) Virus Antigen - Premium (BA112VS) (strain Moscow B-4), we have developed three excellent antigens for TBEV assay development. Virion\Serion’s native Tick-borne encephalitis (TBE) Virus Antigen - Premium is cultured in Vero cells and purified by size exclusion chromatography.

All antigens are suitable for the detection of IgG and IgM antibodies against TBE.

Please  let us know if you are interested in 0.25 mg test samples.