Varicella Zoster Virus (VZV)
Varicella Zoster Virus is a Herpesvirus belonging to the Herpesviridae family and is closely related to human HSV-1 and HSV-2. It causes chickenpox (varicella) in children and herpes zoster (shingles) in adults. VZV is a worldwide spread pathogen, also known as human Herpesvirus Type 3 (HHV-3). For production of the two different native antigens offered, Varicella Zoster Virus (strain Ellen) is cultivated in HEL 299 cells and purified by ultra-centrifugation through a sucrose cushion or via affinity chromatography to purify the viral glycoproteins. The lysate antigen (prepared by ultra-centrifugation) is recommended for the detection of IgM antibodies while the glycoprotein based antigen is recommended for the detection of IgG antibodies against VZV.
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